The Preclinical Testing Gap: Why Drug Discovery Is Failing
90% of drug candidates fail in human trials—because outdated models don't predict real outcomes.

Revolutionizing Preclinical Drug Testing with Human-First Models
Caleo Biotechnologies’ patient-derived DOD technology provides a predictive, scalable model for drug development.

Human-First, Patient-Derived Models
Moving beyond outdated animal testing with advanced, biologically relevant disease models.

Multi-Cellular Complexity for Accuracy
Integrates epithelial, stromal, and immune cells to replicate disease behavior with unmatched precision.

Higher Predictive Power, Fewer Failures
Delivers more reliable preclinical testing, reducing costly late-stage drug failures in clinical trials.

Scalable Platform for Future Diseases
Starting with IBD, expanding to other diseases, shaping the future of precision medicine and drug discovery.
Unmatched Performance. Proven Results.
From Patient Tissues to Breakthroughs — Redefining Drug Testing with Human Biology.

95% better decisions with human-first drug models.
Bringing the future of drug testing to life—where every decision is backed by patient-derived data.
Redefining Drug Success
Human-first models uncover real treatment potential, reducing failures and accelerating breakthroughs.
Designed for the Industry. Built for Smarter, Human-First Drug Development.
Trusted by Science. Validated by Innovation.
Backed by Leading Research, Built for Real-World Impact.
Caleo Biotechnologies collaborates with top researchers, institutions, and industry leaders to set new standards in human-first drug development—delivering scientifically validated, high-impact solutions that drive the future of medicine.
Scientific Integrity
Our technology is built on peer-reviewed research and cutting-edge advancements, ensuring every model meets the highest standards of accuracy and reliability.
Industry Validation
Partnered with leading biotech and pharmaceutical innovators, our models are tested, trusted, and integrated into the next generation of drug development.